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KMID : 0828520070110030162
Journal of the Korean Geriatrics Society
2007 Volume.11 No. 3 p.162 ~ p.166
Pyridostigmine for Treatment of Acute Colonic Pseudo-obstruction(Ogilvies syndrome) in a Older Patient on CAPD
Choi Jun-Hyouck

Nam Yang-Hoon
Seo In-Seok
Lim Ji-Hwan
Jang Yoo-Hyun
Kim Bong-Roung
Yoon Su-Jin
Kim Hyuk-Jung
Abstract
In acute colonic pseudo-obstruction(Ogilvie¡¯s syndrome, 1948), there is no distal obstruction but colonic obstruction symptom and distended colon is shown radiologicaly and clinically. The etiology of this syndrome are complex of any medical and surgical problem. Elderly patients who are undergoing CAPD have multiple medical problems. But among them only one case which was diagnosed with this syndrome was reported in Korea. Neostigmine is unstable medicine due to muscarinic effects if neostigmine(anticholinesterase inhibitor) has side effects to the CAPD patients with multiple medical problems, it can be fatal. We use pyridostigmine, which has less muscarinic effect, and has similiar potency compared to neostigmine to acute colonic pseudo-obstruction, and thus achieved radiological improvement.
KEYWORD
Colonic pseudo-obstruction, Pyridostigmine, Continuous Ambulatory Peritoneal Dialysis(CAPD)
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